BST2 negatively regulates porcine reproductive and respiratory syndrome virus replication by restricting the expression of viral proteins

Yujiao Zhang,Ning Kong,Jinfeng Ti, Dongshen Cao, Zhaofeng Sui,Aimin Ge, Liuting Pan,Kuan Zhao,Yanjun Zhou,Guangzhi Tong,Liwei Li,Fei Gao

Virus Research（2023）

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摘要

•Bone marrow stromal cell antigen 2 (BST2) can inhibit viral replication.•BST2 exhibits significant anti-PRRSV activity.•BST2 expression is up-regulated during the early phase of infection.•BST2 restricts the expression of viral proteins.

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关键词

respiratory syndrome virus replication,viral proteins

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