Predictive value of serum lncRNA MALAT1 for the recurrence of persistent atrial fibrillation after radiofrequency ablation.

Biomarkers in medicine(2023)

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摘要
The authors investigated the predictive value of for persistent atrial fibrillation (PAF) recurrence after radiofrequency ablation. Serum level was determined. The correlation between and high-sensitivity C-reactive protein/left atrial diameter (LAD) was analyzed. The predictive value of MALAT1 was evaluated. The postoperative recurrence rate in patients with high/low was compared. Independent risk factors for postoperative recurrence were analyzed. was elevated in PAF patients and positively correlated with high-sensitivity C-reactive protein/LAD. /high-sensitivity C-reactive protein/LAD were enhanced in patients with recurrent PAF. Patients with high had a higher recurrence rate. Upregulated was an independent risk factor for postoperative PAF recurrence. Serum level >2.03 predicts postoperative recurrence of PAF, and PAF patients with high have a higher risk of postoperative recurrence.
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关键词
correlation analysis, high-sensitivity C-reactive protein, Kaplan-Meier, left atrial dimension, lncRNA MALAT1, logistic regression analysis, persistent atrial fibrillation, receiver operating characteristic curve
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