Dendritic Cell-Derived Exosomes Driven Drug Co-Delivery Biomimetic Nanosystem for Effective Combination of Malignant Melanoma Immunotherapy and Gene Therapy.

Jiecheng Lin, Na Huang,Mingjuan Li, Mengyuan Zheng,Zhuoxiang Wang, Xiaojuan Zhang, Huan Gao, Yunzhe Lao,Jie Zhang,Baoyue Ding

Drug design, development and therapy（2023）

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摘要

The study suggests that the siBRAF-mDexo biomimetic drug codelivery system can be used to effectively treat MM, which provides a new strategy for combined gene therapy and immunotherapy for MM.

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关键词

malignant melanoma immunotherapy,cell-derived,co-delivery

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