Hypoglycaemia induces a sustained pro-inflammatory response in people with type 1 diabetes and healthy controls.

Clementine E M Verhulst,Julia I P van Heck,Therese W Fabricius,Rinke Stienstra,Steven Teerenstra,Rory J McCrimmon,Cees J Tack,Ulrik Pedersen-Bjergaard,Bastiaan E de Galan

Diabetes, obesity & metabolism（2023）

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摘要

Overall, despite differences in prior exposure to hypoglycaemia, the pattern of the inflammatory responses to hypoglycaemia did not differ between people with type 1 diabetes and healthy controls. In conclusion, hypoglycaemia induces a range of pro-inflammatory responses that are sustained for at least 1 week in people with type 1 diabetes and healthy controls.

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关键词

clamp, counterregulatory hormones, C-reactive protein, diabetes, hypoglycaemia, inflammation, white blood cells

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