Dimethyl fumarate-related immune and transcriptional signature is associated with clinical response in multiple sclerosis-treated patients.

Alicia Sánchez-Sanz,Santiago García-Martín,Julia Sabín-Muñoz,Irene Moreno-Torres,Víctor Elvira,Fátima Al-Shahrour,Aranzazu García-Grande,Elvira Ramil,Ofir Rodríguez-De la Fuente,Beatriz Brea-Álvarez,Ruth García-Hernández,Antonio García-Merino,Antonio José Sánchez-López

Frontiers in immunology（2023）

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摘要

Responder patients to DMF exhibit differences in monocyte and lymphocyte subpopulations and a distinguishable transcriptomic response compared to non-responders that should be further studied for the validation of biomarkers of treatment response to DMF.

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关键词

transcriptional signature,dimethyl,fumarate-related,sclerosis-treated

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