Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire.

Eliza M Gordon-Lipkin,Payal Banerjee,Jose Luis Marin Franco, Tatiana Tarasenko,Shannon Kruk,Elizabeth Thompson,Derek E Gildea,Suiyuan Zhang,Tyra G Wolfsberg,Willy A Flegel,Peter J McGuire

Frontiers in immunology（2023）

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摘要

Overall, we show that children with MtD display perturbations in the B cell repertoire which may impact humoral immunity and the ability to clear viral infections.

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primary oxidative phosphorylation defects

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