Assessment of BoHV-4-based vector vaccine intranasally administered in a hamster challenge model of lung disease.

Seok-Chan Park,Laura Conti,Valentina Franceschi,Byungkwan Oh,Myeon-Sik Yang, Gaeul Ham,Antonino Di Lorenzo,Elisabetta Bolli,Federica Cavallo,Bumseok Kim,Gaetano Donofrio

Frontiers in immunology（2023）

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摘要

These results suggested that intranasal immunization with BoHV-4-BV induced protective immunity and that BoHV-4-BV could be a potential vaccine platform for the protection of other animal species against respiratory diseases.

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关键词

vaccine, lung disease, BoHV-4-based vector, intranasal vaccination, immune response

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