Analysis of the association of HER-2 low carcinomas and PAM50 assay in hormone receptor positive early-stage breast cancer.

Santiago Terán,Manuel Alva,Pablo Tolosa,Macarena Rey-Cárdenas,Ainhoa Madariaga,Laura Lema,Yolanda Ruano,Luis Manso,Eva Ciruelos,Rodrigo Sánchez-Bayona

Breast (Edinburgh, Scotland)（2023）

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摘要

In this early-stage breast cancer cohort, HER2-low was not associated with a high-risk PAM50 compared to HER2-zero carcinomas. Ki-67 ≥ 20%, T2/T3, histological grade 2/3, N+ and PR<20% were significantly associated to a high-risk PAM50.

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关键词

breast cancer,hormone receptor,low carcinomas,pam50,early-stage

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