Biology activity and characterization of the functional L-HN fragment derivative of botulinum neurotoxin serotype E.

Xiao Tan,Cong-Cong Zhang,Jian-Sheng Lu,Zhi-Ying Li,Bo-Lin Li,Xu-Yang Liu,Yun-Zhou Yu,Qing Xu

Anaerobe（2023）

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摘要

The EL-HN fragment showed good biological activities in vivo and in vitro, and could be used as a drug screening model and to further explore the molecular mechanism of its transmembrane transport.

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关键词

Botulinum neurotoxin, L-HN fragment, Neurotoxicity, Neuro-2a, SNAP-25, SV2C

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