Central nervous system sulfatide deficiency as a causal factor for bladder disorder in Alzheimer's disease.

Sijia He,Shulan Qiu,Meixia Pan,Juan P Palavicini,Hu Wang,Xin Li,Anindita Bhattacharjee, Savannah Barannikov,Kevin F Bieniek,Jeffrey L Dupree,Xianlin Han

Clinical and translational medicine（2023）

引用 1|浏览9

暂无评分

摘要

Our study identified CNS ST deficiency as a causal factor for AD-like lipid dysregulation, inflammation response and ultimately the development of bladder disorders. Targeting to maintain ST levels may serve as a promising strategy for the prevention and treatment of AD-related peripheral disorders.

查看译文

关键词

Alzheimer's disease, bladder, lipidome, spinal cord, sulfatide

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要