Robustness of CSF Aβ42/40 and Aβ42/P-tau181 measured using fully automated immunoassays to detect AD-related outcomes.

Antoine Leuzy,Niklas Mattsson-Carlgren,Nicholas C Cullen,Erik Stomrud,Sebastian Palmqvist,Renaud La Joie,Leonardo Iaccarino,Henrik Zetterberg,Gil Rabinovici,Kaj Blennow,Shorena Janelidze,Oskar Hansson

Alzheimer's & dementia : the journal of the Alzheimer's Association（2023）

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摘要

CSF Aβ42/p-tau181 was more robust to the effects of measurement variability, suggesting that it may be the preferred Elecsys-based measure in clinical practice and trials.

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