RIPK3-MLKL necroptotic signalling amplifies STING pathway and exacerbates lethal sepsis.
Clinical and translational medicine(2023)
摘要
These findings elucidate molecular mechanisms linking necroptosis to the STING pathway, and suggest a potential benefit of therapeutic targeting of necroptosis in STING-driven inflammatory diseases.
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关键词
amplifies sting pathway,ripk3–mlkl
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