Immunohistochemical Surrogates for Molecular Stratification in Medulloblastoma.

Dheeraj Chinnam,Aastha Saraswati, Swathi Jogunoori, Aanchal Verma,Tanvi Kiran,Pravin Salunke,Nalini Gupta,Narendra Kumar,Renu Madan,Bishan Dass Radotra,Kirti Gupta

Applied immunohistochemistry & molecular morphology : AIMM（2023）

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摘要

Molecular stratification significantly contributes to prognostication, and a panel of 3 antibodies is helpful in stratifying MB into its subgroups in centers where access to advanced molecular testing is limited. Our study reinforces the efficacy of incorporating this cost-effective, minimal panel into routine practice for stratification. Further, we propose a 3-risk stratification grouping, incorporating morphology and molecular markers.

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medulloblastoma,immunohistochemical surrogates,molecular stratification

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