The rs72613567:TA polymorphism in HSD17B13 is associated with survival benefit after development of hepatocellular carcinoma.

Hamish Innes,Marsha Y Morgan,Jochen Hampe,Felix Stickel,Stephan Buch

Alimentary pharmacology & therapeutics（2023）

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摘要

The rs72613567:TA polymorphism in HSD17B13 is not only associated with a reduction in the risk of developing HCC but with a survival benefit in HCC once established. Therapeutic inhibition of HSD17B13 may augment survival in individuals with HCC.

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关键词

cirrhosis, genetic factors, genetic susceptibility, liver cancer, mortality, prognosis, therapeutic target

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