Exploring the impact of hippocampal sclerosis on white matter tracts memory in individuals with mesial temporal lobe epilepsy.

Tamires A Zanao,Johanna Seitz-Holland,Lauren J O'Donnell,Fan Zhang,Yogesh Rathi,Tátila M Lopes,Luciana Ramalho Pimentel-Silva,Clarissa L Yassuda,Nikos Makris,Martha E Shenton,Sylvain Bouix,Amanda E Lyall,Fernando Cendes

Epilepsia open（2023）

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摘要

Our results highlight that the presence and side of HS are crucial to understand the pathophysiology of MTLE. Specifically, left-sided HS seems to be related to widespread bilateral white matter abnormalities. Future longitudinal studies should focus on developing diagnostic and treatment strategies dependent on HS's presence/side.

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hippocampal sclerosis,epilepsy,white matter tracts,memory

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