Comorbid alcohol use disorder and post-traumatic stress disorder: A proof-of-concept randomized placebo-controlled trial with buprenorphine and naltrexone combination treatment.

Lori L Davis,Ismene L Petrakis,Patricia D Pilkinton,Tracy Nolen,Nathan Vandergrift,Shawn Hirsch,Seth D Norrholm,Thomas R Kosten

Alcohol (Hanover, York County, Pa.)（2023）

引用 0|浏览10

暂无评分

摘要

This is the first study to evaluate the potential of κ-opioid receptor antagonism for the treatment of comorbid AUD and PTSD. The combination of buprenorphine and naltrexone-XR showed no significant improvement over placebo for the composite, PTSD or alcohol measures.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要