Metformin restores cognitive dysfunction and histopathological deficits in an animal model of sporadic Alzheimer's disease

Saghar Rabieipoor,Meysam Zare,Miren Ettcheto,Antoni Camins,Mohammad Javan

Heliyon（2023）

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摘要

Metformin decreased inflammatory cells and reactive astrocytes as well as the dying neurons in the hippocampus region and the cortex in SAD, and improved the cognitive performance.

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关键词

alzheimer disease,sporadic alzheimer,cognitive dysfunction,histopathological deficits

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