Barrier films for the prevention of acute radiation dermatitis in breast cancer: A systematic review and meta-analysis of randomised controlled trials

•Meta-analysis of 5 trials investigating Hydrofilm® and Mepitel® barrier films.•Reduction of incidence and severity of radiation dermatitis and moist desquamation.•Fewer patient-reported pain, itching, burning, and limitations in daily activities.•Mild and self-limiting side effects, high acceptance, favourable cost-benefit ratio.•Mainly Caucasian patients and limited information on radiation treatment techniques.