Cellular Composition of Right Atrial and Right Ventricular Samples from Pediatric Patients with Congenital Heart Disease

Background: The molecular nature of congenital heart disease (CHD) is still not well understood. Single nuclei RNA sequencing (SN-RNAseq) is a state-of-the-art technique to analyze the molecular complexity of tissues. We sought to compare the cellular composition of right atrial and right ventricular cardiac biopsies from pediatric CHD patients at the single cell level.