PCR171 Longitudinal Patterns of Adherence for Oral Endocrine Therapy Among US Women with Breast Cancer: A Group-Based Trajectory Modeling Study

Breast cancer (BC) is one of the leading causes of cancer death among American women. Oral endocrine therapy (OET) including tamoxifen and aromatase inhibitors (AIs) reduces recurrence risk and is associated with better disease-free and overall survival in hormone receptor-positive (HR+) BC patients. However, poor adherence of up to 50-60% contributes to recurrences in about one-third of patients. This study aimed to evaluate longitudinal patterns of adherence to OET using a group-based trajectory model (GBTM).