SARS-CoV-2 infection dysregulates NAD metabolism.

Amin Izadpanah,Joseph C Mudd,Joe G N Garcia,Sudesh Srivastav,Mohamed Abdel-Mohsen,Clovis Palmer,Aaron R Goldman,Jay K Kolls,Xuebin Qin,Jay Rappaport

Frontiers in immunology（2023）

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摘要

Our data suggest that infection perturbs NAD pathways, identify novel mechanisms that may explain some pathophysiology of CoVID-19 and suggest novel strategies for both treatment and prevention.

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关键词

COVID-19, NAD, metabolism, PASC, NAMPT, sirtuins

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