Downregulation of monocyte miRNAs: implications for immune dysfunction and disease severity in drug-resistant tuberculosis.

Pavithra Sampath,Manju Moorthy,Athul Menon, Lekshmi Madhav, Aishwarya Janaki,Madhavan Dhanapal,Alangudi Palaniappan Natarajan,Syed Hissar,Uma Devi Ranganathan, Gopalakrishna Ramaswamy,Ramalingam Bethunaickan

Frontiers in immunology（2023）

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摘要

Thus, monocyte miRNA signatures provide pathological clues for altered monocyte function, drug resistance, and disease severity. Further studies on monocyte miRNAs may shed light on the immune regulatory mechanism for tuberculosis.

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关键词

monocyte mirnas,tuberculosis,immune dysfunction,drug-resistant

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