Linear energy transfer-inclusive models of brainstem necrosis following proton therapy of paediatric ependymoma.

Andreas H Handeland,Daniel J Indelicato,Lars Fredrik Fjæra,Kristian S Ytre-Hauge,Helge Egil S Pettersen,Ludvig P Muren,Yasmin Lassen-Ramshad,Camilla H Stokkevåg

Physics and imaging in radiation oncology（2023）

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摘要

The established models of brainstem necrosis illustrate a potential impact of high LET regions in patients receiving high doses to the brainstem, and thereby support LET mitigation during clinical treatment planning.

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关键词

proton therapy,brainstem necrosis,transfer-inclusive

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