Pretreatment lymphocyte-to-monocyte ratio as a prognostic factor and influence on dose-effect in fractionated stereotactic radiotherapy for oligometastatic brain metastases in non-small cell lung cancer patients.

Tian Chen,Mengqiu Tang, Yang Zhou, Zhepei Wang, Shiwei Li,Hongcai Wang, Yangfang Lu, Jinguo Wang,Weiyu Shen

Frontiers in oncology（2023）

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摘要

LMR is an independent prognostic factor of i-LCS and OS in NSCLC patients with brain oligo-metastasis treated with FSRT. Patients with tumor diameter ≥ 2 and LMR < 4 should be treated with BED10 greater than 53.6Gy.

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关键词

lymphocyte to monocyte ratio (LMR), biologically effective dose (BED), brain oligo-metastasis, fractionated stereotactic radiotherapy (FSRT), intracranial local control survival (i-LCS)

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