In vivo labeling of nascent viral HBV and HDV RNA for investigating viral replication and clearance kinetics

Jonathan Kolbe,Tassilo Volz,Annika Volmari,Lena Allweiss,Katja Giersch,Marc Lütgehetmann,Maura Dandri

Zeitschrift Fur Gastroenterologie（2023）

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摘要

Background/Aim Labeling of newly synthesized RNA is a promising approach to investigate viral replication kinetics and stability of viral components in circulation. We aimed to label nascent host and viral transcripts in vivo to gain insights into replication dynamics and stability of HBV and HDV.

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关键词

hdv rna,nascent viral hbv,viral replication,vivo labeling

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