Long-term follow-up in robot-assisted female cystectomy: an international multi-center study

You have accessJournal of UrologyCME1 Apr 2023MP46-17 LONG-TERM FOLLOW-UP IN ROBOT-ASSISTED FEMALE CYSTECTOMY: AN INTERNATIONAL MULTI-CENTER STUDY Linda Dey, Monish Aron, Jorge Ballon, Giovanni E. Cacciamani, Mihir M. Desai, Inderbir S. Gill, Abolfazl Hosseini, Arad Hosseini, Etienne Lavallee, Reza Mehrazin, Gus Miranda, Juhana Rautiola, Jordan Rich, John Sfakianos, Viktor Skokic, Gunnar Steineck, Yuan Shuo Wang, and Peter Wiklund Linda DeyLinda Dey More articles by this author , Monish AronMonish Aron More articles by this author , Jorge BallonJorge Ballon More articles by this author , Giovanni E. CacciamaniGiovanni E. Cacciamani More articles by this author , Mihir M. DesaiMihir M. Desai More articles by this author , Inderbir S. GillInderbir S. Gill More articles by this author , Abolfazl HosseiniAbolfazl Hosseini More articles by this author , Arad HosseiniArad Hosseini More articles by this author , Etienne LavalleeEtienne Lavallee More articles by this author , Reza MehrazinReza Mehrazin More articles by this author , Gus MirandaGus Miranda More articles by this author , Juhana RautiolaJuhana Rautiola More articles by this author , Jordan RichJordan Rich More articles by this author , John SfakianosJohn Sfakianos More articles by this author , Viktor SkokicViktor Skokic More articles by this author , Gunnar SteineckGunnar Steineck More articles by this author , Yuan Shuo WangYuan Shuo Wang More articles by this author , and Peter WiklundPeter Wiklund More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003292.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Approximately one quarter of all bladder-cancer patients are females, and studies indicate that female patients may have an inferior oncological outcome. Radical cystectomy is the gold standard treatment for aggressive bladder cancer. However, the long-term outcome for females after robot-assisted radical cystectomy (RARC) is not well described in the scientific literature. Objectives: To describe the long-term oncological outcomes and complications after RARC in female patients. METHODS: In total, 270 females undergoing RARC due to urothelial cancer at 3 high-volume centers (Karolinska University Hospital, The Mount Sinai Hospital and USC) during 2004 to 2020 were followed. Data include age, cT-, pT-, N-, and M-stage, smoking, urinary diversion, and surgical strategy for pelvic organ preservation (POP). Outcome data for early and late complications according to Clavien-Dindo, readmission, re-operation, and cause of death were obtained. Median follow-up time was 952 days (inter-quartile range, 279 - 2089 days). RESULTS: Muscle invasive bladder cancer (MIBC; 71.5%) was more prevalent than non-muscle invasive bladder cancer (NMIBC; 24.9%). Fifteen percent received a neobladder and 17.7% underwent POP. Cancer-specific death (CSD) was 20.7% during the follow-up period (Figure 1). No patients with TIS grade cancer died from cancer during follow-up, while higher cT-stage was associated with earlier CSD. For cT-stages 1-4, CSD ceases over time. Complication-free surgery was reported for 52.6% (early) and 82.2% (late) of patients. The incidence of early complications by Clavien-Dindo were 35.1% for I-II and 12.3% for III or higher, respectively. Readmission within 30 days was 22.2% and re-operation within 30 days was 1.5%. CONCLUSIONS: The oncological outcome in our data appear to have no clear differences with published male cystectomy series. Also, the complication rates among women undergoing robot-assisted radical cystectomy seems comparable to other published series. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e639 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Linda Dey More articles by this author Monish Aron More articles by this author Jorge Ballon More articles by this author Giovanni E. Cacciamani More articles by this author Mihir M. Desai More articles by this author Inderbir S. Gill More articles by this author Abolfazl Hosseini More articles by this author Arad Hosseini More articles by this author Etienne Lavallee More articles by this author Reza Mehrazin More articles by this author Gus Miranda More articles by this author Juhana Rautiola More articles by this author Jordan Rich More articles by this author John Sfakianos More articles by this author Viktor Skokic More articles by this author Gunnar Steineck More articles by this author Yuan Shuo Wang More articles by this author Peter Wiklund More articles by this author Expand All Advertisement PDF downloadLoading ...