Cutaneous Ureterostomy Following Radical Cystectomy for Bladder Cancer: A Contemporary Series

Reza Nabavizadeh, Rodrigo Rodrigues Pessoa, Mihai G. Dumbrava,Vignesh T. Packiam,Prabin Thapa, Robert Tarrell, Matthew K. Tollefson,R. Jeffrey Karnes, Igor Frank, Abhinav Khanna, Paras Shah, Vidit Sharma,Stephen A. Boorjian

UROLOGY(2023)

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摘要
OBJECTIVE To report peri-operative outcomes of a contemporary series of bladder cancer patients under-going radical cystectomy (RC) with cutaneous ureterostomy (CU) urinary diversion at a tertiary referral center.METHODS We retrospectively identified patients who underwent RC with CU at Mayo Clinic between 2016 and 2021. Clinicopathologic and perioperative characteristics were analyzed using standard descriptive statistics.RESULTS A total of 31 patients underwent RC with CU at our institution. Median age was 72 years and 21 were male. This was highly comorbid cohort (83% had an American Society of Anesthesiologists [ASA] Physical Status Classification System >= 3; median Charlson Comorbidity index = 8). Median time to flatus, tolerating regular diet, and length of stay were 3 (interquartile range [IQR] 3-3), 3 (IQR 3-4), and 4 days (IQR 4-7), respectively. A total of 14 patients experienced a high-grade complication (Clavien-Dindo >= 3) within 30 days of surgery, and 8 were readmitted. The most common 30-day complication was sepsis, which affected 13% (4/31) of patients. At 90 days postsurgery, the readmission rate was 32% (10/31), most com-monly for sepsis. Three patients required reoperation within 90 days, including one patient who required CU revision due to stomal ischemia. One patient died within this time frame from causes unrelated to bladder cancer.CONCLUSION In a comorbid, relatively elderly bladder cancer cohort undergoing RC, the use of CU was associated with expeditious surgery and postoperative recovery. CU represents an option for urinary diversion in high-risk patients undergoing RC. Higher rate of postoperative ureteral obstruction can be pre-emptively addressed with chronic stent placement.
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