Mp56-04 contemporary oncologic, functional, and complications outcomes of robot-assisted radical cystectomy with totally intracorporeal neobladder diversion

You have accessJournal of UrologyCME1 Apr 2023MP56-04 CONTEMPORARY ONCOLOGIC, FUNCTIONAL, AND COMPLICATIONS OUTCOMES OF ROBOT-ASSISTED RADICAL CYSTECTOMY WITH TOTALLY INTRACORPOREAL NEOBLADDER DIVERSION Jordan Rich, Etienne Lavalle, Yuon Shuo Wang, Kyrollis Attalla, Linda Dey, Stockholm, Sweden, Monish Aron, Giovannia Cacciamani, Jorge Ballon, Mihir Desai, Inderbir Gill, Abolfazl Hosseini, Arad Hosseini, Stockholm, Sweden, Gus Miranda, Juhana Rautiola, Viktor Skokic, Gunnar Steinbeck, Reza Mehrazin, John Sfakianos, and Peter Wiklund Jordan RichJordan Rich More articles by this author , Etienne LavalleEtienne Lavalle More articles by this author , Yuon Shuo WangYuon Shuo Wang More articles by this author , Kyrollis AttallaKyrollis Attalla More articles by this author , Linda DeyLinda Dey More articles by this author , Stockholm Stockholm More articles by this author , Sweden Sweden More articles by this author , Monish AronMonish Aron More articles by this author , Giovannia CacciamaniGiovannia Cacciamani More articles by this author , Jorge BallonJorge Ballon More articles by this author , Mihir DesaiMihir Desai More articles by this author , Inderbir GillInderbir Gill More articles by this author , Abolfazl HosseiniAbolfazl Hosseini More articles by this author , Arad HosseiniArad Hosseini More articles by this author , Stockholm Stockholm More articles by this author , Sweden Sweden More articles by this author , Gus MirandaGus Miranda More articles by this author , Juhana RautiolaJuhana Rautiola More articles by this author , Viktor SkokicViktor Skokic More articles by this author , Gunnar SteinbeckGunnar Steinbeck More articles by this author , Reza MehrazinReza Mehrazin More articles by this author , John SfakianosJohn Sfakianos More articles by this author , and Peter WiklundPeter Wiklund More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003309.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: We aim to present oncologic, functional, and complications outcomes for patients undergoing Robot-assisted radical cystectomy (RARC) from a large multi-institutional cystectomy cohort. METHODS: Data from patients who underwent RARC with intracorporeal neobladder diversion between 2003-2022 from our multi-national, multi-institutional cohort were prospectively collected. Baseline demographic and clinical characteristics as well as oncologic, complications and functional outcomes were analyzed. Survival rates were estimated with Kaplan-Meier plots. RESULTS: Of 359 patients, 319 (88.9%) were male. Mean (SD) age was 62.8 (9.4) and BMI was 26.8 (4.2). The cohort included 33 (9.2%) pTa or pTis, 104 (29.1%) pT1, 185 (51.8%) pT2, 31 (8.7%) pT3, and 4 (1.1%) pT4 bladder tumors preoperatively. Median [IQR] follow-up time was 17.6 mo [9.3, 38.5]. We recorded positive margins in 4 (1.1%) patients. Clavien 3-5 complications occurred in 59 (16.4%) and 96 (27.3%) patients within 30 and 90 days, respectively. Clavien <3 complications occurred in 130 (35.2%) and 199 (55.4%) patients within 30 and 90 days, respectively. Kaplan-Meier estimates for recurrence free, cancer-specific, and overall survival at 24 mo were 76.7%, 87.6%, and 86.2% respectively. Percentage of patients requiring 0, 1, or>1 pad for daytime continence at 12 mo was 72.4%, 9.6%, and 18% respectively for men, and 38.1%, 9.5%, and 52.4% respectively for women. Percentage of patients requiring 0, 1, or>1 pad for nighttime continence at 12 mo was 24.5%, 34.2%, and 41.3% respectively for men and 25%, 35%, and 40% respectively for women. The percentage of patients requiring 0-1 pads for daytime and nighttime continence at 12 mo was 82.9% and 60.2%, respectively with nerve sparing, compared to 72.7% and 40.9%, respectively without nerve sparing. When nerve sparing technique was utilized, potency at 12 mo without assistance and with a PDE-5 inhibitor was 41.2% and 75.4%, respectively. CONCLUSIONS: We report outcomes for RARC with intracorporeal neobladder diversion from a multi-institutional cohort. Importantly, oncologic, complications, and functional outcomes appear non-inferior to prior open series, with improvements in functional outcomes using nerve-sparing technique. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e774 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jordan Rich More articles by this author Etienne Lavalle More articles by this author Yuon Shuo Wang More articles by this author Kyrollis Attalla More articles by this author Linda Dey More articles by this author Stockholm More articles by this author Sweden More articles by this author Monish Aron More articles by this author Giovannia Cacciamani More articles by this author Jorge Ballon More articles by this author Mihir Desai More articles by this author Inderbir Gill More articles by this author Abolfazl Hosseini More articles by this author Arad Hosseini More articles by this author Stockholm More articles by this author Sweden More articles by this author Gus Miranda More articles by this author Juhana Rautiola More articles by this author Viktor Skokic More articles by this author Gunnar Steinbeck More articles by this author Reza Mehrazin More articles by this author John Sfakianos More articles by this author Peter Wiklund More articles by this author Expand All Advertisement PDF downloadLoading ...