Acupotomy ameliorates subchondral bone absorption and mechanical properties in rabbits with knee osteoarthritis by regulating bone morphogenetic protein 2-Smad1 pathway.

Chen Xilin,Guo Yan,L U Juan,Qin Luxue,H U Tingyao, Zeng Xin,Wang Xinyue,Zhang Anran,Zhuang Yuxin, Zhong Honggang,Guo Changqing

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan（2023）

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摘要

Acupotomy could effectively protect cartilage by inhibiting abnormal bone resorption and improving mechanical properties of subchondral bone thorough the related proteins of BMP2-Smad1 pathway in KOA rabbits.

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关键词

acupuncture therapy, osteoarthritis, knee, subchondral bone, mechanical properties, bone morphogenetic protein 2, Smad1 protein

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