Protection of a novel velvet antler polypeptide PNP1 against cerebral ischemia-reperfusion injury.

Hongyan Pei,Rui Du, Zhongmie He,Yi Yang,Shasha Wu,Wenyan Li,Jian Sheng, Yahui Lv,Chenyang Han

International journal of biological macromolecules（2023）

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摘要

Velvet antler polypeptide PNP1 isolated in this study has the anti-ischemic cerebral injury effect, and its mechanism is associated with suppressing vascular endothelial cell injury and microglial cell inflammatory response.

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关键词

Antler polypeptide,Microglial cells,Ischemia reperfusion,Vascular endothelial cells,Inflammation

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