Effects of FODMAPs and Gluten on Gut Microbiota and Their Association with the Metabolome in Irritable Bowel Syndrome: A Double-Blind, Randomized, Cross-Over Intervention Study.

Elise Nordin,Per M Hellström,Johan Dicksved,Erik Pelve,Rikard Landberg,Carl Brunius

Nutrients（2023）

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摘要

FODMAPs, but not gluten, altered microbiota composition and correlated with phenolic-derived metabolites and 3-indolepropionate, with only weak associations with IBS symptoms. Thus, the minor effect of FODMAPs on IBS symptoms must be weighed against the effect on microbiota and metabolites related to positive health factors.

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关键词

irritable bowel syndrome, FODMAPs, gluten, gut microbiota, SCFAs, metabolome, multiomics

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