PI3K/AKT pathway-related microRNA variants in childhood acute lymphoblastic leukemia.

Yao Xue,Xiaoyan Sun,Jinyu Fu,Liucheng Rong,Heng Zhang,Yuting Zhu,Xiaoyun Yang,Shaoyan Hu,Jing Chen,Yongjun Fang

Pediatric blood & cancer（2023）

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摘要

Our study highlights the significant association between the miR-149 rs2292832 genetic variant and childhood ALL susceptibility in the Chinese population. These findings expand our understanding of the complex genetic landscape underlying ALL and have implications for the development of personalized therapeutic strategies.

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