Sex-specific inflammatory markers of risk and presence of depression in adolescents.

Zuzanna Zajkowska,Naghmeh Nikkheslat,Pedro H Manfro,Laila Souza,Fernanda Rohrsetzer,Anna Viduani,Rivka Pereira,Jader Piccin,Valentina Zonca,Annabel E L Walsh,Nancy Gullett,Helen L Fisher,Johnna R Swartz,Brandon A Kohrt,Christian Kieling,Valeria Mondelli

Journal of affective disorders（2023）

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摘要

Our findings suggest sex-specific associations between inflammatory markers and the development of adolescent depression, where IL-2 may increase risk for depression and severity of depressive symptoms in boys, but not in girls. However, IL-6 may increase risk for more severe depressive symptoms in girls.

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关键词

Depression,Depressive symptoms,Adolescence,Inflammation,Sex differences,Cytokines

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