Mp51-06 safety and efficacy of greenlight pvp in octogenarians: evaluation of the global greenlight group database

You have accessJournal of UrologyCME1 Apr 2023MP51-06 SAFETY AND EFFICACY OF GREENLIGHT PVP IN OCTOGENARIANS: EVALUATION OF THE GLOBAL GREENLIGHT GROUP DATABASE Claudia Deyirmendjian, David-Dan Nguyen, Kyle Law, Anna-Lisa Nguyen, Iman Sadri, Adel Arezki, David Bouhadana, Ahmed Ibrahim, Naeem Bhojani, Dean Elterman, Bilal Chughtai, Franck Bruyere, Luca Cindolo, Giovanni Ferrari, Carlos Vasquez-Lastra, Tiago Borelli-Bovo, Edgardo Becher, Hannes Cash, Maximillian Reimann, Enrique Rijo, Vincent Misrai, and Kevin Zorn Claudia DeyirmendjianClaudia Deyirmendjian More articles by this author , David-Dan NguyenDavid-Dan Nguyen More articles by this author , Kyle LawKyle Law More articles by this author , Anna-Lisa NguyenAnna-Lisa Nguyen More articles by this author , Iman SadriIman Sadri More articles by this author , Adel ArezkiAdel Arezki More articles by this author , David BouhadanaDavid Bouhadana More articles by this author , Ahmed IbrahimAhmed Ibrahim More articles by this author , Naeem BhojaniNaeem Bhojani More articles by this author , Dean EltermanDean Elterman More articles by this author , Bilal ChughtaiBilal Chughtai More articles by this author , Franck BruyereFranck Bruyere More articles by this author , Luca CindoloLuca Cindolo More articles by this author , Giovanni FerrariGiovanni Ferrari More articles by this author , Carlos Vasquez-LastraCarlos Vasquez-Lastra More articles by this author , Tiago Borelli-BovoTiago Borelli-Bovo More articles by this author , Edgardo BecherEdgardo Becher More articles by this author , Hannes CashHannes Cash More articles by this author , Maximillian ReimannMaximillian Reimann More articles by this author , Enrique RijoEnrique Rijo More articles by this author , Vincent MisraiVincent Misrai More articles by this author , and Kevin ZornKevin Zorn More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003299.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: GreenLight photoselective vaporization of the prostate (PVP) is a surgical treatment for benign prostatic hyperplasia (BPH) that yields comparable results to transurethral resection of the prostate while demonstrating lower postoperative bleeding rates. However, granular data is lacking for patients above the age of 80. Considering the aging patient population, there is a need to further characterize outcomes in elderly patients. The present study analyzes the largest international GreenLight database, the Global GreenLight Group (GGG), to evaluate the functional and safety profile of GreenLight PVP in octogenarians. METHODS: The GGG is a database comprised of patients that underwent GreenLight PVP from 2011 to 2019 performed by 8 experienced high-volume urologists at 7 different international hospitals. Patients 80 years or older at the time of surgery were categorized as octogenarians. They were compared to a similar group of patients undergoing PVP below the age of 80. RESULTS: Among 3,648 patients, 586 (16%) men were above the age of 80. Compared to patients under the age of 80, octogenarians had larger prostates (76.0 ml vs 71.9 ml, p=0.02) and a lower BMI (25.6 vs 26.7, p=0.045). They also had higher ASA scores: 61.0% were considered high-medical-risk compared to 22.7% in those under the age of 80. Operative time was not significantly longer in octogenarians compared to the control group. The improvement in functional outcomes between 80-year-old patients and control patients was not significantly different at one-year follow-up, with the exception of maximum urinary flow (Qmax) that favoured younger patients. The changes in functional outcomes between octogenarians and control patients can be found in Table 1. The odds of transfusion were greater for older patients [OR 8.2 (95% CI 3.6–18.9, p<0.01)], but they were not at increased risk of hematuria. Moreover, octogenarians had higher hospital readmission rates (23.0% vs 11.9%, p<0.01). CONCLUSIONS: GreenLight PVP is an effective surgical option for treating symptomatic BPH in octogenarians and achieves similar functional outcomes compared to younger patients. The odds of transfusion were higher in patients over 80, but the absolute risk remains low. The 30-day hospital readmission rate however was higher in octogenarians. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e694 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Claudia Deyirmendjian More articles by this author David-Dan Nguyen More articles by this author Kyle Law More articles by this author Anna-Lisa Nguyen More articles by this author Iman Sadri More articles by this author Adel Arezki More articles by this author David Bouhadana More articles by this author Ahmed Ibrahim More articles by this author Naeem Bhojani More articles by this author Dean Elterman More articles by this author Bilal Chughtai More articles by this author Franck Bruyere More articles by this author Luca Cindolo More articles by this author Giovanni Ferrari More articles by this author Carlos Vasquez-Lastra More articles by this author Tiago Borelli-Bovo More articles by this author Edgardo Becher More articles by this author Hannes Cash More articles by this author Maximillian Reimann More articles by this author Enrique Rijo More articles by this author Vincent Misrai More articles by this author Kevin Zorn More articles by this author Expand All Advertisement PDF downloadLoading ...