Single-cell profiling reveals distinct immune response landscapes in tuberculous pleural effusion and non-TPE.

Xinting Yang, Jun Yan,Yu Xue, Qing Sun,Yun Zhang,Ru Guo,Chaohong Wang,Xuelian Li,Qingtao Liang,Hangyu Wu, Chong Wang,Xinlei Liao,Sibo Long,Maike Zheng,Rongrong Wei,Haoran Zhang,Yi Liu,Nanying Che,Laurence Don Wai Luu,Junhua Pan,Guirong Wang,Yi Wang

Frontiers in immunology（2023）

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摘要

We provide a tissue immune landscape of PF immune cells, and revealed a distinct local immune response in TPE and non-TPE (TSPE and MPE). These findings will improve our understanding of local TB immunopathogenesis and provide potential targets for TB therapy.

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关键词

tuberculous pleural effusion,distinct immune response landscapes,single-cell,non-tpe

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