Comprehensive investigation of clinicopathological and immunological features to determine prognostic impact in metastatic renal cell carcinoma: The JEWEL study.

Kojiro Ohba,Keisuke Monji,Takahiro Osawa,Kazutoshi Yamana,Yosuke Yasuda,Hajime Tanaka,Yuki Nakagawa,Tamaki Fukuyama,Nobuaki Matsubara,Hirotsugu Uemura,Hideki Sakai,Masatoshi Eto

International journal of urology : official journal of the Japanese Urological Association（2023）

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摘要

JEWEL identified sex, age, ECOG PS, liver and bone metastases, CRP levels, WHO/ISUP grade, LDH, and albumin levels as key prognostic factors for OS after first-line TKI therapy for mRCC.

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Cox proportional hazards model, multivariate analysis, prognostic factors, renal cell carcinoma, tyrosine kinase inhibitors

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