A high Z-score might increase the positive predictive value of cell-free noninvasive prenatal testing for singleton-pregnant women.

Li Ma,Yulan Li, Lei Li, Hong Wu,Yongming Liu,Xin Yang,Aimin Lin

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians（2023）

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摘要

Z-score is associated with the PPV performance of NIPT in fetal T13, T18, and T21. The possibility of false positives caused by placental chimerism should be considered when determining whether high Z-values lead to high PPVs.

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positive predictive value,z-score,cell-free,singleton-pregnant

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