Network connectivity alterations across the MAPT mutation clinical spectrum. Liwen Zhang , Taru M Flagan , Suvi Häkkinen , Stephanie A Chu , Jesse A Brown , Alex J Lee , Lorenzo Pasquini , Maria Luisa Mandelli , Maria Luisa Gorno-Tempini , Virginia E Sturm , Jennifer S Yokoyama , Brian S Appleby , Yann Cobigo , Bradford C Dickerson , Kimiko Domoto-Reilly , Daniel H Geschwind , Nupur Ghoshal , Neill R Graff-Radford , Murray Grossman , Ging-Yuek Robin Hsiung , Edward D Huey , Kejal Kantarci , Argentina Lario Lago , Irene Litvan , Ian R Mackenzie , Mario F Mendez , Chiadi U Onyike , Eliana Marisa Ramos , Erik D Roberson , Maria Carmela Tartaglia , Arthur W Toga , Sandra Weintraub , Zbigniew K Wszolek , Leah K Forsberg , Hilary W Heuer , Bradley F Boeve , Adam L Boxer , Howard J Rosen , Bruce L Miller , William W Seeley , Suzee E Lee Annals of neurology(2023)
摘要
Network connectivity alterations arise as early as the presymptomatic phase. Future studies will determine whether presymptomatic carriers' baseline connectivity profiles predict symptomatic conversion. This article is protected by copyright. All rights reserved.
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