Targeted treatment in a case series of AR+, HRAS/PIK3CA co-mutated salivary duct carcinoma.

Damian T Rieke,Sebastian Schröder,Philippe Schafhausen,Eric Blanc,Erika Zuljan,Benjamin von der Emde,Dieter Beule,Ulrich Keller,Ulrich Keilholz,Konrad Klinghammer

Frontiers in oncology（2023）

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摘要

Available data further support comprehensive molecular profiling of SDC. Combination therapies, PI3K-inhibitors and immune therapy warrant further investigation, ideally in clinical trials. Future research should consider this rare subgroup of SDC.

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关键词

salivary gland cancer, salivary duct carcinoma, targeted therapy, precision oncology, molecular tumor board, head and neck cancer

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