Does Post-traumatic Stress Disorder Impact Treatment Outcomes within a Randomised Controlled Trial of Mitochondrial Agents for Bipolar Depression?

Samantha E Russell,Anna L Wrobel,Melanie M Ashton,Alyna Turner,Mohammadreza Mohebbi,Michael Berk,Sue Cotton,Seetal Dodd,Chee H Ng,Gin S Malhi,Olivia M Dean

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology（2023）

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摘要

There were no differences in clinical outcomes over time within the context of an adjunctive randomised controlled trial between those with bipolar disorder alone compared to those with comorbid bipolar disorder and post-traumatic stress disorder. However, differences in psychosocial factors may provide targets for areas of specific support for people with comorbid bipolar disorder and post-traumatic stress disorder.

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bipolar depression,mitochondrial agents,randomised controlled trial,treatment,post-traumatic

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