Differences in clinical outcomes based on molecular markers in glioblastoma patients treated with concurrent tumor-treating fields and chemoradiation: exploratory analysis of the SPARE trial.

Louis Cappelli, Mehak Majid Khan,Allison Kayne,Spencer Poiset,Ryan Miller,Ayesha Ali,Muneeb Niazi,Wenyin Shi,Iyad Alnahhas

Chinese clinical oncology（2023）

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摘要

Leveraging the molecular characterization of GBM alongside advancing treatments such as chemoradiation with TTF presents a new opportunity to improve precision oncology and outcomes for GBM patients.

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关键词

Glioblastoma (GBM), tumor-treating fields, O6-methylguanine-DNA methyltransferase (MGMT), telomerase reverse transcriptase (TERT)

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