Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing.

Chuan-Bao Zhang,Zhi-Liang Wang,Han-Jie Liu,Zheng Wang,Wang Jia

Frontiers in neurology（2023）

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摘要

TARA infiltration might promote glioma tumor progression and can be used as a diagnostic, predictive and prognostic marker in gliomas. Prevention of TARA infiltration might be a new therapeutic strategy for glioma.

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关键词

reactive astrocytes, glioma, molecular and genomic features, immunotherapy, sequencing

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