Assessment of mortality-related risk factors and effective antimicrobial regimens for treatment of bloodstream infections caused by carbapenem-resistant Pseudomonas aeruginosa in patients with hematological diseases.

Sisi Zhen,Yuanqi Zhao,Zhangjie Chen,Tingting Zhang,Jieru Wang,Erlie Jiang,Fengkui Zhang,Yingchang Mi,Xiaofan Zhu,Mingzhe Han,Zhijian Xiao,Jianxiang Wang,Sizhou Feng

Frontiers in cellular and infection microbiology（2023）

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摘要

For patients with hematological diseases and CRPA bacteremia, 30-day mortality rate was 21.0% (21/100). Neutropenia >7 days after BSI, higher Pitt bacteremia score, higher Charlson comorbidity index and bacteremia due to MDR-PA increased 30-day mortality. CAZ-AVI-based regimens were effective alternatives for bacteremia due to CRPA or MDR-PA.

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关键词

multidrug-resistant Pseudomonas aeruginosa, bacteremia, ceftazidime-avibactam, hematological diseases, carbapenem-resistant Pseudomonas aeruginosa

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