Influence of PD-L1 expression on the efficacy of EGFR-TKIs in EGFR-mutant non-small cell lung cancer.

Si-Yu Lei,Hai-Yan Xu,Hong-Shuai Li,Ya-Ning Yang,Fei Xu,Jun-Ling Li,Zhi-Jie Wang,Pu-Yuan Xing,Xue-Zhi Hao,Yan Wang

Thoracic cancer（2023）

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摘要

The efficacy of EGFR-TKIs was influenced by the baseline PD-L1 expression. Higher PD-L1 expression was associated with shorter PFS. The combined indicators of TP53 and PD-L1 identified subgroups showing divergent benefits from EGFR-TKIs.

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关键词

efficacy, epidermal growth factor receptor, programmed death-ligand 1, tumor protein 53, tyrosine kinase inhibitors

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