Development of hybrid immunity during a period of high incidence of Omicron infections.

Anja Frei,Marco Kaufmann,Rebecca Amati,Audrey Butty Dettwiler,Viktor von Wyl,Anna Maria Annoni,Julia Vincentini,Céline Pellaton,Giuseppe Pantaleo,Jan S Fehr,Valérie D'Acremont,Murielle Bochud,Emiliano Albanese,Milo A Puhan

International journal of epidemiology（2023）

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摘要

This first study on functional and hybrid immunity in the Swiss general population after Omicron waves showed that SARS-CoV-2 has become endemic. The high levels of antibodies and neutralization support the emerging recommendations of some countries where booster vaccinations are still strongly recommended for vulnerable persons but less so for the general population.

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关键词

SARS-CoV-2, COVID-19, hybrid immunity, functional immunity, seroprevalence, neutralization, vaccination, infection, cohort, population-based

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