Noninvasive investigations of human glymphatic dynamics in a diseased model.

Chia-Hung Wu,Yu Kuo,Feng-Chi Chang,Jiing-Feng Lirng,Yu-Hsiang Ling,Yen-Feng Wang,Hsiu-Mei Wu,Jong-Ling Fuh,Chung-Jung Lin,Shuu-Jiun Wang,Shih-Pin Chen

European radiology（2023）

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摘要

• This study aimed to investigate the human glymphatic dynamics in a noninvasive diseased model. • The intracranial MR-detectable gadolinium-based contrast agents were removed centrifugally within 961 to 1086 min. • The glymphatic dynamics was demonstrable by enhancing MRI in an in vivo diseased model noninvasively.

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关键词

Contrast media, Gadolinium, Blood-brain barrier, Magnetic resonance imaging, Vasoconstriction

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