Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma.

Lei Cheng,Wanru Duan,Jian Guan,Kai Wang,Zhenlei Liu,Xingwen Wang,Zuowei Wang,Hao Wu,Zan Chen,Fengzeng Jian

Neurospine（2023）

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摘要

CSF-based liquid biopsy showed potential feasibility for molecular analysis of primary intramedullary astrocytoma through sequencing of ctDNA. This approach may assist in diagnosis and prognostic evaluation of this rare spinal cord tumor.

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关键词

circulating tumor dna,cerebrospinal fluid,glioma-related,csf-based

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