Long-term weight changes after starting anti-IL-5/5Ra biologics in severe asthma: the role of oral corticosteroids.
The journal of allergy and clinical immunology. In practice（2023）
摘要
Anti-IL-5/5Ra therapy is associated with long-term weight reduction, especially in patients with higher OCS exposure prior to and those able to reduce OCS use during treatment. However the effect is small and does not apply to all patients, so additional interventions seem necessary if weight change is desired.
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关键词
Severe asthma, Eosinophilic asthma, Airway inflammation, Biologics, Corticosteroids, Body mass index, Extrapulmonary traits, Multicenter
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