Protection against brain injury after ischemic stroke by intravenous human amnion epithelial cells in combination with tissue plasminogen activator.

Liz J Barreto-Arce,Hyun Ah Kim,Siow Teng Chan,Rebecca Lim,Grant R Drummond,Henry Ma,Thanh G Phan,Christopher G Sobey,Shenpeng R Zhang

Frontiers in neuroscience（2023）

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摘要

When administered following tPA in acute stroke, hAECs improve safety and attenuate infarct growth in association with less BBB disruption and lower 24 h mortality.

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关键词

ischemic stroke, neuroprotection, thrombolytic, stem cells, mouse, inflammation

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