AAV-CRISPR-Cas13 eliminates human enterovirus and prevents death of infected mice.

Choong Tat Keng,Thinesshwary Yogarajah,Regina Ching Hua Lee, Irfan Bin Hajis Muhammad,Bing Shao Chia, Suraj Rajan Vasandani,Daryl Shern Lim,Ke Guo,Yi Hao Wong,Chee Keng Mok,Justin Jang Hann Chu,Wei Leong Chew

EBioMedicine（2023）

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摘要

Agency for Science, Technology and Research (A∗STAR) Assured Research Budget, A∗STAR Central Research Fund UIBR SC18/21-1089UI, A∗STAR Industrial Alignment Fund Pre-Positioning (IAF-PP) grant H17/01/a0/012, MOE Tier 2 2017 (MOE2017-T2-1-078; MOE-T2EP30221-0005), and NUHSRO/2020/050/RO5+5/NUHS-COVID/4.

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关键词

Adeno-associated viral vectors,CRISPR-Cas13d,Bioinformatics,Enterovirus,Prophylactic,Therapeutic

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